Memory loss associated with marijuana use is caused by the drug's interference with the brain's natural protein synthesis machinery, according to a new study by European researchers.
Posted on Mon, 03 Aug 2009 00:00:00 EDT at
http://www.sciencedaily.com/releases/200...123240.htm
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Thank for share this link. Very useful to this causes.Memory loss associated with marijuana use is caused by the drug's interference with the brain's natural protein synthesis machinery, according to a study published in Nature Neuroscience.
The scientists found that THC increases the activity of a pathway that promotes protein synthesis in the mouse brain. This transient increase of protein synthesis was mediated specifically by cannabinoid receptors expressed on the brain's inhibitory neurons, and correlated with long-term memory deficits in mice. Interestingly, the authors also found that inhibition of this signaling pathway by rapamycin, an immunosuppressant drug used to prevent organ rejection following transplantation, prevents THC-induced amnesia in mice.